CUBOSOMES: A BOON FOR COSMECEUTICALS AND TOPICAL DRUG DELIVERY

Cubosomes are the nanoparticles of bicontinuous, lyotropic cubic phases, comprised curved lipid bilayers organized into a three-dimensional honeycomb (cavernous) like structures separating two internal aqueous channels and large interfacial area. Cubic phases optically isotropic, very viscous, solid-like (crystalline) with crystallographic symmetry. They can encapsulate hydrophilic, hydrophobic amphiphilic drug substances, which able to target control release bioactive agent. The cosmetic industry has made progress in development products overcome skin as barrier deliver actives through effectively. Drug incorporated cubosomes shows some unique advantageous like, protection from chemical physiological degradation, vivo controlled manner improving bioavailability while reducing side effect. pharmacologically inactive, non-irritant, non-toxic, effective, cosmetically acceptable. Topical delivery drugs selectively specific site; this avoids fluctuations levels improves patient compliance suitable local systemic therapeutic effects. Cubosomal topical formulation outstanding potential advantages for their sustained delivery. This review article mainly focuses on applications cubosomes.